BMAC – Orthopaedics and Rehabilitation Excellence of Miami

Bone Marrow Aspirate Concentrate Stem Cell Therapy

WHAT IS REGENERATIVE ORTHOPAEDIC TREATMENT?

From traumatic injuries to sports activities to repetitive day-to-day life duties, we put our bodies through a lot of wear and tear. The joints, tendons, and cartilage in the major joints of our extremities absorb the bulk of this stress, and unfortunately, these tissues have limited ability to heal on their own. Several conditions can cause pain, such as traumatic injury, repetitive overuse, or degenerative arthritis.

Regenerative Orthopaedic treatments are a non-surgical, natural treatment option using the healing power of your bone marrow concentrate to accelerate healing, repair damaged tissues, improve range of motion, and address pain. Regenerative orthopaedic Bone Marrow Aspirate Concentrate (BMAC) injections use stem cells, growth factors, and other signaling compounds to jump-start and accelerate your body’s natural healing systems.

Bone Marrow Aspirate Concentrate (BMAC) treatments harness the healing power of your own body to overcome musculoskeletal injury, pain, or osteoarthritis. The process involves a harvest or aspiration of bone marrow, a centrifugation process to separate out your stem cells, and re-injection of your bone marrow concentrate (BMAC) under ultrasound guidance, fluoroscopic radiography, or needle arthroscopy.

BMAC contains a high concentration of stem cells, growth factors, proteins, and othersignaling compounds. Bone marrow is a rich source of stem cells, which can replicate into cartilage cells, skeletal muscle, and bone cells. The stem cell are able to promote growth and healing of the target tissue using localized cellular environment factors that direct the appropriate cell to differentiate and promote. When introduced into a damaged area, these unique compounds act by promoting tissue healing and signaling other molecules to recruit even more stem cells and healing compounds to the area, facilitating repair of the damaged tissues.

BMAC is prepared from a bone marrow aspiration spun at a very high rate of speed to concentrate the stem cells and growth factors. We use the Emcyte PureBMC® processing system to ensure the highest concentration of stem cells and growth factors to maximize the healing power of your BMAC.

WHY CHOOSE DR. WILKERSON?

We take a different approach to musculoskeletal pain and injury at Orthopaedics and Rehabilitation Excellence of Miami. Dr. Wilkerson is a board certified orthropaedicsurgeon and with over two decades of experience treating patient with orthobiologics and regenerative orthopaedic medicine treatments. We are constantly searching for the most advanced and effective strategies in regenerative medicine. We have established safe and effective protocols utilizing BMAC to treat degenerative conditions, overuse repetitive injuries, and traumatic injuries.

STEM CELL THERAPY WITH BONE MARROW ASPIRATE CONCENTRATE FOR EXTREMITY INJURY BENEFITS

BMAC uses your own stem cells and growth factors to initiate the repair of the ligaments, tendons, or cartilage. These regenerative treatments may allow you to delay the need for surgery or decrease the necessity for medication.

WHAT RESULTS TO EXPECT:

• Reduced joint pain

• Improved range of motion

• Better mobility

• Less reliance on over-the-counter or prescription medication

• Reduced inflammation

STEM CELL THERAPY WITH BONE MARROW ASPIRATE CONCENTRATE FOR BACK INJURY BENEFITS

Bone Marrow Aspirate Concentrate (BMAC) treatment for back injury uses your stem cells and growth factors to initiate the repair of the ligaments, tendons, cartilage, or discs in the spine. These regenerative treatments may allow you to delay the need for surgery or decrease the need for medication.

WHAT RESULTS TO EXPECT:

• Reduced joint pain

• Improved range of motion

• Better mobility

• Avoidance of surgery

• Increased strength

• Better posture

• Less reliance on over the counter or prescription medication

• Reduced inflammation

HOW LONG WILL RESULTS LAST?

Bone Marrow Aspirate Concentrate (BMAC) treatments do not offer instant pain relief but regenerate injured or damaged tissue over time. Clinical studies and our patients report that the effect of regenerative orthopedic therapy for pain or injury lasts anywhere from two to five years. This depends on the severity of the damage. Depending on your situation, we may recommend more than one BMAC treatment or follow-up injections of PRP to prolong results.

COST & PRICING STRUCTURE

Bone Marrow Aspirate Concentrate (BMAC) treatments are priced based on the amount of BMAC needed, the area(s) treated, and the type of injury treated. Sometimes a PRP injection booster is recommended following treatment. Our regenerative medicine experts will determine the specifics at your personalized consultation.

HOW THE PROCEDURE WORKS

Our goal is to provide our patients with customized care and individualized treatment strategies based on their overall health. Our regenerative treatments can improve the quality of life for our patients suffering from shoulder pain or injury.

Bone Marrow Aspirate Concentrate (BMAC) procedures are same-day outpatient treatments that take place at our accredited office procedure room.

BEFORE & PREPARATION

• Initially, you will see Dr. Wilkerson or one of our regenerative medicine providers to determine if you are an appropriate candidate for the procedure.

• We may perform or order diagnostic tests (radiographs, MRI scans, or ultrasound scans) to determine your eligibility for treatment.

• Please bring any available existing diagnostic imaging to your appointment. If possible bring the report and images for review.

• Avoid all anti-inflammatory medications like Aleve, Motrin, Advil, and cortisone seven days before treatment.

• Notify your provider if you take any blood thinners.

• Eat a light meal one to two hours before treatment.

• Drink 6-8 glasses of water the day before and on the day of treatment.

• Avoid smoking five to seven days before and after treatment. Smoking will impair your healing process.

DURING THE PROCEDURE

• First, board-certified physicians perform a bone marrow extraction from your hip under local anesthesia using ultrasound or fluoroscopy guidance.

• We use well-established protocols and processing methods to concentrate the stem cells and growth factors by spinning the sample at high speed.

• The BMAC is injected into your musculoskeletal injury with ultrasound,fluoroscopy, or needle arthroscopy guidance. This will ensure that the exact location of the injury or pain is treated.

• The procedure takes about two hours from start to finish. Follow-up visits to monitor progress occurs one month, three months, and six months following treatment.

• For enhanced results, a PRP injection booster may be recommended.

AFTERCARE & RECOVERY

• Bone Marrow Aspirate Concentrate (BMAC) injections are designed to produce a micro-injury in the treatment area.

• It is common to experience stiffness, soreness, swelling, or slight pain, which decreases in intensity over time.

• Avoid anti-inflammatory medications or supplements for six to twelve weeks following treatment.

• Avoid steroid medications.

• Do not apply ice to the treatment area. Ice decreases inflammation, which stops the healing process.

• Keep the treatment area as still as possible for 30-60 minutes post-injection.

• You may shower 12 hours following treatment. Avoid baths, hot tubs, etc., for the first three days after treatment.

• Do the gentle range of motion activities provided.

• Physical therapy may be recommended.

AM I A CANDIDATE FOR REGENERATIVE ORTHOPEDIC BMAC STEM CELL INJECTION?

Bone Marrow Aspirate Concentrate (BMAC) Stem Cell injection may be a suitable option for those with musculoskeletal injury or pain who:

• Experience reduced range of motion in the shoulder, hip, and knee

• Experience joint stiffness

• Feel like their joint is unstable or gives out

• Feel or hear a “grinding” sensation when the joint is in motion

• Do not respond to standard treatment protocols

• Desire natural or alternative treatments options to surgery

• Suffer from pain or injury to ligaments, muscles, tendons, or cartilage

Bone Marrow Aspirate Concentrate (BMAC) Stem Cell injection can help you get back to the life you enjoy sooner without the risks, pain, prolonged recovery time, and limited effectiveness of surgery.

TREATMENT AREAS/CONDITIONS

Conditions that respond well to Bone Marrow Aspirate Concentrate (BMAC) stem cell injection include:

Shoulder	Elbow	Wrist & Hand
• Shoulder instability • Rotator cuff injury • Labrum tears • Rotator Cuff Impingement • Biceps Tendonitis • Tendinosis • Osteoarthritis	• Joint instability, • Lateral epicondylitis (tennis elbow) • Medial epicondylitis (golfer’s elbow) • Osteoarthritis • Ulnar Collateral ligament Sprain	• Carpal tunnel syndrome • Trigger finger • CMC arthritis • Triangular fibrocartilage complex (TFCC) injury. • Tendonitis
Hip	Knee	Ankle & Foot
• Labral Tear • Hip impingement • Trochanteric Bursitis • Hip Tendonitis • Hip Abductor Injury • Hip Adductor Injury • Osteoarthritis	• ACL Sprain • Meniscus Tear • MCL Sprain • LCL Sprain • Chondromalacia • Patella tendonitis • Quad Tendonitis • Osteoarthritis	• Ankle instability • Ligament sprain • Ligament tear • AchillesTendonitis • Plantar fasciitis • Peroneus Tendon Tear • Posterior Tibialis Tendon Tear • Osteoarthritis

RELATED PROCEDURES….

• PRP injection: PRP or platelet-rich plasma harnesses the healing power of the platelets found in your blood to overcome joint pain or injury.

• Arthroscopic Surgery: Outpatient arthroscopic orthopaedic surgery that repairs repairs or reconstructs torn cartilage, ligaments, tendons, or muscles will benefit from both improved and accelerated healing potential with postoperative BMAC stem cell, PRP, or . These injections are staged 2 to 4 weeks after the initial surgical procedure.

• Cortisone steroid injection: Cortisone is a steroid commonly used to treat soft tissue inflammation and arthritic joint issues. However, over time it contributes to the weakening of collagen fibers and destruction of the joint. Cortisone steroid injections due not repair torn tendons, cartilage, or bone.

Contraindications To Bone Marrow Aspirate Concentrate

The following may exclude you from BMAC treatment:

• Anemia

• Low platelet count

• Abnormal platelet function

• Active infection

• Active cancer

• Anticoagulant medication therapy

• Clotting disorders